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For the 2025-26 school year, there are 2 public schools serving 701 students in Santee, SC.

The top-ranked public school in Santee, SC is Lake Marion High School. Overall testing rank is based on a school's combined math and reading proficiency test score ranking.

Santee, SC public schools have an average math proficiency score of 52% (versus the South Carolina public school average of 43%), and reading proficiency score of 72% (versus the 52% statewide average). Schools in Santee have an average ranking of 9/10, which is in the top 20% of South Carolina public schools.

Minority enrollment is 91% of the student body (majority Black), which is more than the South Carolina public school average of 53% (majority Black).